TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.0000500nMAssay Description:Transactivation of human PPARalpha expressed in human HepG2 cells cotransfected with PPRE3-TK-Luc by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.0000600nMAssay Description:Transactivation of human PPARalpha expressed in human HepG2 cells cotransfected with PPRE3-TK-Luc by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.0000700nMAssay Description:Transactivation of human PPARalpha expressed in human HepG2 cells cotransfected with PPRE3-TK-Luc by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.000310nMAssay Description:Transactivation of human PPARalpha expressed in human HepG2 cells cotransfected with PPRE3-TK-Luc by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.00380nMAssay Description:Agonist activity at human PPARalpha transactivation expressed in human HePG2 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.0260nMAssay Description:Transactivation of human PPARalpha expressed in human HepG2 cells cotransfected with PPRE3-TK-Luc by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.0300nMAssay Description:Agonist activity at PPARalpha (unknown origin) expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assa...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.0720nMAssay Description:Agonist activity at PPARalpha (unknown origin) expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assa...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.0890nMAssay Description:Agonist activity at PPARalpha (unknown origin) expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assa...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.100nMAssay Description:Transactivation of human PPARalpha expressed in human HepG2 cells cotransfected with PPRE3-TK-Luc by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.160nMAssay Description:Agonist activity at GAL4-tagged PPARalpha ligand-binding domain (unknown origin) expressed in HEK293T cells incubated for 16 to 19 hrs by beta-lactam...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.272nMAssay Description:Agonist activity at PPARalpha (unknown origin) expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assa...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.300nMAssay Description:Agonist activity at human PPARalpha assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.600nMAssay Description:Agonist activity at PPARalpha (unknown origin) expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assa...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.600nMAssay Description:Activation of PPARalpha transfected in HEK293 cells after 18 hrs by firefly luciferase reporter gene-based luminescence assay relative to controlMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.615nMAssay Description:Transcriptional activation activity on human T279M-mutant Peroxisome proliferator activated receptor alpha expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.650nMAssay Description:Agonist activity at PPARalpha in human HepG2 cellsMore data for this Ligand-Target Pair
Ligand InfoPDB
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.850nMAssay Description:Agonist activity at Gal4-fused human PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.870nMAssay Description:Agonist activity at Gal4-fused human PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.890nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.950nMAssay Description:Agonist activity at Gal4-fused human PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at human PPAR-alpha expressed in CHO-K1 cells by PathHunter assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at Gal4-fused PPARalpha LBD (unknown origin) transfected in human HepG2 cells assessed as transcriptional activation incubated for 2...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:In vitro transcriptional activation in CV-1 cells expressing human Gal4-PPAR alpha ligand binding domainMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Transactivation of GAL4-fused Homo sapiens (human) PPARalpha DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Transactivation of GAL4-fused Homo sapiens (human) PPARalpha DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at GAL4 tagged human PPARalpha ligand binding domain expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at GAL4 tagged human PPARalpha ligand binding domain expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Transcriptional activation of reporter assay by human Peroxisome proliferator activated receptor alpha in CV-1 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at GAL4-tagged PPARalpha ligand-binding domain (unknown origin) expressed in HEK293T cells incubated for 16 to 19 hrs by beta-lactam...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Transactivation by human PPAR alpha in COS1 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Transactivation of Homo sapiens (human) PPARalpha assessed as luciferase activity by reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at Gal4-fused human PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at Gal4-fused human PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at human PPARalpha transactivation expressed in human HePG2 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at human PPARalpha in U2OS cells by transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at human recombinant PPARalpha by GAL4 transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at human recombinant PPARalpha by GAL4 transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at human recombinant PPARalpha by GAL4 transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at human recombinant PPARalpha by GAL4 transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at human recombinant PPARalpha by GAL4 transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1.09nMAssay Description:Agonist activity at PPARalpha (unknown origin) expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assa...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1.10nMAssay Description:Agonist activity at GAL4-tagged PPARalpha ligand-binding domain (unknown origin) expressed in HEK293T cells incubated for 16 to 19 hrs by beta-lactam...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1.30nMAssay Description:The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. EC50 is the concentration...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1.33nMAssay Description:HEK293 cells were incubated in DMEM medium containing 10% of fetal bovine serum at 37° C. in the presence of 5% of CO2. 3×105/ml cells were plated in...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1.40nMAssay Description:Agonist activity at PPARalpha (unknown origin)More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1.5nMAssay Description:Agonist activity at Gal4-fused human PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1.70nMAssay Description:Agonist activity at GAL4-fused PPARalpha assessed as transcriptional activity by cell based assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1.80nMAssay Description:Displacement of pan-PPAR fluormone from PPARalpha LBD by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1.90nMAssay Description:Transactivation of human PPARalpha expressed in human HepG2 cells cotransfected with PPRE3-TK-Luc by luciferase reporter gene assayMore data for this Ligand-Target Pair